This package provides prof(1), the protein secondary structure, accessibility
and transmembrane helix predictor from Burkhard Rost. Prediction is either
done from protein sequence alone or from an alignment - the latter should be
used for optimal performance.
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How well does prof(1) perform?
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* Secondary structure is predicted at an expected average accuracy > 72% for
the three states helix, strand and loop.
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* Solvent accessibility is predicted at a correlation coefficient
(correlation between experimentally observed and predicted relative
solvent accessibility) of 0.54
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* Transmembrane helix prediction has an expected per-residue accuracy of
about 95%. The number of false positives, i.e., transmembrane helices
predicted in globular proteins, is about 2%.
Installed Size: 26.8 MB
Architectures: all