Eagle estimates haplotype phase either within a genotyped cohort or using a
phased reference panel. The basic idea of the Eagle1 algorithm is to harness
identity-by-descent among distant relatives—which is pervasive at very large
sample sizes but rare among smaller numbers of samples—to rapidly call phase
using a fast scoring approach. In contrast, the Eagle2 algorithm analyzes a
full probabilistic model similar to the diploid Li-Stephens model used by
previous HMM-based methods.
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This package provides some example data for eagle.
Installed Size: 1.6 MB
Architectures: all