xpore - 2.1-1 main

RNA is transcribed from DNA, possibly spliced and exported to the
cytoplasm - fine - but its bases can also be modified, edited, and
not all such modifications are visible by Sanger sequencing methods
and its derivatives.
.
The Nanopore measures potentials, and if the bases have a different
shape then this is measured - not necessarily in an interpretable manner,
something must be left for mass spectrometry, but one may be pointed
to a difference. And maybe one can even statistically associate such
differences with a molecular or clinical phenotype.