abPOA is an extended version of Partial Order Alignment (POA) that performs
adaptive banded dynamic programming (DP) with an SIMD implementation. abPOA
can perform multiple sequence alignment (MSA) on a set of input sequences and
generate a consensus sequence by applying the heaviest bundling algorithm to
the final alignment graph.
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abPOA can generate high-quality consensus sequences from error-prone long
reads and offer significant speed improvement over existing tools.
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abPOA supports three alignment modes (global, local, extension) and flexible
scoring schemes that allow linear, affine and convex gap penalties. It right
now supports SSE2/SSE4.1/AVX2 vectorization.
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For more information please refer to the paper[1] published in Bioinformatics.
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[1]: https://dx.doi.org/10.1093/bioinformatics/btaa963
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